Doc-To-Help Enterprise 2007 supports two types of source documents: Word and HTML. In addition to allowing you to build help targets from Word documents, Doc-To-Help gives you the option of building a help target directly from HTML documents, without even using Word, or you can add both Word and HTML documents to the same project.
When you create a new project, you can select which type of documents you want to use.
Note: Doc-To-Help Enterprise 2007 supports HTML source documents, cascading style sheets and FrontPage and Dreamweaver integration. Doc-To-Help for Word 2007 does not support these features.
More:
Single and Multiple Topic Documents
Adding a Document to a Project